Maternal marijuana use could have lifelong effects on unborn

Offspring of pregnant lab mice subjected to doses of THC, the main active ingredient in marijuana or cannabis, exhibited effects lasting a lifetime, according to a study published in the official journal of the National Academy of Sciences.

Mice, like humans, are naturally equipped to receive cannabinoids, the chemical compounds found in marijuana. The primary cannabinoid receptor, CB1, sends signals to the brain, but when that signaling was interrupted by THC, or tetrahydrocannabinol, its full development was never realized in the in utero mice, even into adulthood.

Unlike humans, mice have very high concentrations of cannabinoid receptors where motor skills and coordination of movement are developed. That partially explains why it’s difficult to know the full implications for humans of this study, which was carried out by scientists from Complutense University of Madrid, Spain. Besides being a potential red flag for recreational marijuana use, this study could have implications for...

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